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Objective

Awareness of pharmacometrics techniques and their potential to improve the efficiency of drug development is swiftly increasing. Learning resources for aspirant pharmacometricians, especially graduate students are limited.

The objective of this free for all site is to aid in pharmacometrics training.


Letter from past ACCP President


What is Pharmacometrics?

- Pharmacometrics is the science which deals with quantitative description of disease, drug effects and variability.

- Requires proficiency in

  1. Biology of disease
  2. Pharmacokinetics (PK) and Pharmacodynamics (PD)
  3. Statistics
  4. Computational techniques

Why Pharmacometrics?

William J. Jusko, an international leader in the field of Pharmacometrics, noted a few years back that1

"Pharmacometrics lies at the heart of what drug companies do: collecting data from animals, normal volunteers and patients; quantifying it, and then being able to determine what that data mean for optimizing drug efficacy and minimizing toxicity."

"Because of skyrocketing demand, this area of pharmacokinetic and pharmacodynamic pharmacometrics offers some of the highest entry-level salaries in the entire pharmaceutical industry"


Site Map

The design of the site is in such a way that it will be a step by step learning process. With the main objective in the mind, the users are encouraged to proceed to the Theory section and then to the Modeling section.

The Theory section contains glossary of terms used in pharmacometrics with their definitions, detailed explanation of different population PKPD analysis methods, estimation methods and good modeling practices.

The Modeling guides the users through a beginner's tutorial, where different case studies are provided with step by step instructions using different softwares. The section also contains a library, which is constantly updated, of all possible codes for different experimental designs, the users may come across. It also contains a frequently asked questions (FAQ's) section, where answers to commonly asked questions are provided.

The users can also contact us and provide any feedback.


References

1.Dr.Jusko quotes on Pharmacometrics

 

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This page last modified on November 11, 2008

The information provided in this website is for educational purposes only